Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse.

Cell Death Dis · 2022 · PMC8990075 · PMID 35393399

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highly significantno p-value reported

Both signatures stratified patients to low/ high risk groups with highly significant p values (<10 −8 ) (Fig. 7A, B ): CAD-dependent gene regulation was associated with poor outcome.

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