Effects of Vitamin D and Body Mass Index on Disease Risk and Relapse Hazard in Multiple Sclerosis: A Mendelian Randomization Study.

Neurol Neuroimmunol Neuroinflamm · 2022 · PMC8990978 · PMID 35393342

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The correlation between 25OHD and the active form of vitamin D (1,25-dihydroxyvitamin D or calcitriol) is highly significant but limited in magnitude. 53 The small sample size of the available 1,25-dihydroxyvitamin D GWAS limits the power for characterization of 1,25-dihydroxyvitamin D loci. 24 Yet, overlapping genetic associations in the canonical vitamin D metabolic pathway indicate that genetically determined interind

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