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Oligomerization, trans-reduction, and instability of mutant NOTCH3 in inherited vascular dementia.

Commun Biol · 2022 · PMC8991201 · PMID 35393494

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a positive trendno p-value reported
In contrast, the probabilities of obtaining an NEM label at any of the cysteines in the C49Y mutant and R75P mutant were not statistically different from those of WT NOTCH3, although a positive trend was observed at position 9 in the C49Y mutant (Fig. 2d–e ).

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