FIP-nha, a fungal immunomodulatory protein from <i>Nectria haematococca</i>, induces apoptosis and autophagy in human gastric cancer cells via blocking the EGFR-mediated STAT3/Akt signaling pathway.

Food Chem (Oxf) · 2022 · PMC8991989 · PMID 35415679

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The results showed that with the increased dose of FIP-nha, the enzyme precursor of caspase-3 (pro-caspase-3) and caspase-8 (pro-caspase-8) were significantly down-regulated, and the expression of PARP cleavage bands showed an obvious trend of increase ( Fig. 2 C).

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