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Serum lutein is a promising biomarker for type 2 diabetes mellitus and diabetic kidney disease in the elderly.

J Clin Lab Anal · 2022 · PMC8993643 · PMID 35293029

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a decreasing trendno p-value reported
The incidence of DKD showed a decreasing trend with increasing levels of lutein.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.