An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns.

Genome Res · 2022 · PMC8997344 · PMID 35210353

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highly significantno p-value reported

We observed several highly significant associations within the 31 proteins evaluated and enriched significant results (20 with FDR corrected P < 0.05) (see Supplemental Table S1A ).

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