Markers of Maternal Insulin Resistance and Lipid Ratios Measured in Early Pregnancy Are Related to Adverse Fetomaternal Outcomes in Women Treated for Hyperglycemia Detected in Early Pregnancy-Data from a Retrospective Cohort Study.

In the multivariate analysis, both parameters predicted this outcome with a borderline significance (OR for the glucose levels: 1.10 (1.00; 1.22) mg/dL p = 0.058, OR for BMI: 0.39 (0.15; 1.01) p = 0.052), but the model explained a large proportion of the variance of the dependent variable ( p for the model < 0.001, R 2 = 0.72).

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However, these associations failed to reach significance in a multivariate analysis; they explained only a small proportion of the variation in the outcome, and wide confidence intervals indicate that a point estimate was measured in a small study population.

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