DNA methylation regulates TIGIT expression within the melanoma microenvironment, is prognostic for overall survival, and predicts progression-free survival in patients treated with anti-PD-1 immunotherapy.

Clin Epigenetics · 2022 · PMC9004005 · PMID 35410311

Europe PMC DOI

hedged sentence

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantP < 0.001actually significant

Statistical analysis revealed highly significant differences of CpG5 methylation among the different cell subsets ( P < 0.001, ANOVA; Fig. 4 a).

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