Of the 88 O-GlcNAc-modified proteins identified by Ma et al., 62 were found to display increased O-GlcNAcylation in our in vitro reconstitution assay, representing a highly significant over-enrichment (Fig. 5b ).
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The intra-mitochondrial O-GlcNAcylation system rapidly modulates OXPHOS function and ROS release in the heart.
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