almost significantp=0.06
The other two RCTs investigating a low-caloric diet on psoriasis severity did not show significant beneficial effects when compared to no dietary intervention, although the difference in mean PASI change between the low-caloric diet group and control group was almost significant in favor of the low-caloric diet (−2.3 vs −0.3, resp. p=0.06) in the Jensen study (n=60, non-blinded). 29 , 31 Del Giglio (blinded RCT) investigated whether a low-caloric diet (n=22) was able to maintain disease remission after methotrexate (MTX) treatment compared to no dietary intervention (n=20). 29 Mean PASI at the end of the study was not significantly different between the low-caloric group and the control group, but a trend in favor of the low-caloric group was seen.