Lack of Effects of Renin-Angiotensin-Aldosterone System Activity and Beta-Adrenoceptor Pathway Polymorphisms on the Response to Bisoprolol in Hypertension.

Front Cardiovasc Med · 2022 · PMC9010557 · PMID 35433877

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marginally significantno p-value reported

Another study in 2,308 Japanese individuals found a marginally significant difference in the frequencies of the alleles and genotypes between the hypertensives and normotensives, which was more significant in non-heavy smokers ( 40 ).

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