Associations Between Genetic Polymorphisms Within Transporter Genes and Clinical Response to Methotrexate in Chinese Rheumatoid Arthritis Patients: A Pilot Study.

25 In our present study, the major alleles of SLC19A1 rs1051266 and rs2838956 were found to be significantly associated with ΔDAS28-ESR > 0.6 under either dominant model or recessive model, and borderline significant evidence was found for the association of the major allele of SLC19A1 rs1051266 with EULAR good and moderate response under dominant model ( Table S4 ).

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Additionally, the major allele A was associated with increased likelihood of achieving EULAR good and moderate response under the dominant model with borderline significance ( Table S4 ).

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