Conservation and Evolution of Antigenic Determinants of SARS-CoV-2: An Insight for Immune Escape and Vaccine Design.

Front Immunol · 2022 · PMC9014086 · PMID 35444664

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a decreasing trendno p-value reported

In all the variants, the number of escape mutations was found to increase with time to achieve the peak value, and then, a decreasing trend was observed (in Alpha, Beta, Gamma, Iota, and Mu) except for the Delta variant ( Figure 3 ).

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