Rational Design of CRISPR/Cas12a-RPA Based One-Pot COVID-19 Detection with Design of Experiments.

ACS Synth Biol · 2022 · PMC9016756 · PMID 35363475

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

not significantly significantp ≈ 0.06so close (0.05 < p ≤ 0.1)

Although the difference between the 0.5 copy and NSDC was not significantly significant, the p -value was only slightly higher than the threshold ( p ≈ 0.06), which is a promising result for such an extremely low copy number (<1 copy/μL).

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