Design, Synthesis, and Biological Evaluation of [1,2,4]triazolo[4,3-<i>a</i>] Pyrazine Derivatives as Novel Dual c-Met/VEGFR-2 Inhibitors.

Front Chem · 2022 · PMC9019572 · PMID 35464202

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may be significantno p-value reported

For foretinib ( Figure 11A ), the results demonstrated that the residues may be significant for inhibitory effect: MET-1160 (−3.771 kcal/mol) and PHE-1223 (−7.607 kcal/mol).

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