Oral S2-Ag85 DNA Vaccine Activated Intestinal Cell dsDNA and RNA Sensors to Promote the Presentation of Intestinal Antigen.

After receiving S2-Ag85A stimulation, the content of IEC cell signal transduction molecule cGAS was significantly higher than in the control and S2 groups, and cGAMP, TBK1, and IRAK4 showed an increasing trend, while NF- κ B and TRAF6 showed a decreasing trend ( Figure 3 ).

also in 47,180 other papers

After S2-Ag85A stimulation of DC cells, the expression of MCH II was significantly higher than in the control ( P = 0.01) and S2 ( P < 0.05) groups, and the expression of CD11, CD86, CCL5, CD80, and CD103 showed an increasing trend, while the expression of IL-6 decreased. 3.3.

also in 63,971 other papers