Acute Silica Exposure Triggers Pulmonary Inflammation Through Macrophage Pyroptosis: An Experimental Simulation.

Front Immunol · 2022 · PMC9021383 · PMID 35464414

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an increasing trendno p-value reported

As shown in Figure 3A , compared with the control group, the expression of NLRP3, ASC, GSDMD, Caspase-1, IL-1β, and IL-6 was upregulated after ATP treatment, and the majority of these proteins showed an increasing trend after silica exposure, while micro-silica could not upregulate GSDMD of full length (FL).

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