A highly significant correlation ( R 2 = 0.99) between the brain and PBMC O-GlcNAcylation was also seen, implying that peripheral and CNS OGA enzyme activities are equally inhibited by ASN90 ( Figure 2 D).
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O-GlcNAcase Inhibitor ASN90 is a Multimodal Drug Candidate for Tau and α-Synuclein Proteinopathies.
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