FK506-Binding Protein 11 Is a Novel Plasma Cell-Specific Antibody Folding Catalyst with Increased Expression in Idiopathic Pulmonary Fibrosis.

Cells · 2022 · PMC9027113 · PMID 35456020

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.1203

boldest claim

The sentences

just failed significancep = 0.06so close (0.05 < p ≤ 0.1)

We observed a significant ( p = 0.02) but weak negative correlation with FVC (% of predicted) and a similar relationship with DLCO which, however, just failed significance ( p = 0.06; Figure S2 ). 3.2.

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failed to reach significancep = 0.1203not close (p > 0.1)

Western Blot analysis of the hybridoma supernatants suggested a weak reduction of secreted IgG antibody chains for FKBP11 knockdown which, however, failed to reach significance (LC, p = 0.1203; HC, p = 0.2650; paired t -test; Figure 6 H, quantified in Figure 6 G, secreted LC/HC).

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