Hence, a marginally significant correlation between the persistence to ampicillin and nalidixic acid was found in environmental samples of E. coli [ 56 ], but no correlation between the persistence to these two antibiotics and to ciprofloxacin, albeit ciprofloxacin and nalidixic acid share a similar mechanism of action.
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Evolution of Bacterial Persistence to Antibiotics during a 50,000-Generation Experiment in an Antibiotic-Free Environment.
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