Population Pharmacokinetic (Pop-PK) Analysis of Torsemide in Healthy Korean Males Considering CYP2C9 and OATP1B1 Genetic Polymorphisms.

Pharmaceutics · 2022 · PMC9028991 · PMID 35456605

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

might be significantno p-value reported

That is, considering that torsemide is a substrate of OATP1B1 and that OATP1B1 is expressed on the basolateral side of hepatocytes, there might be significant associations between the distribution of torsemide in the body and the genetic polymorphisms of OATP1B1.

also in 2,435 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.