Interestingly, we found a decreasing trend of the ratio long-OPA1/short-OPA1 in sALS compared to Ctrl, suggesting activation of mitophagy in sALS PBMCs ( Figure S1f ) [ 30 ]. 3.2.
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Lysosomes Dysfunction Causes Mitophagy Impairment in PBMCs of Sporadic ALS Patients.
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