RT-PCR and immunofluorescence staining further confirmed the highly significant reduction of TMPRSS2 expression on mRNA and protein levels in SMYD2-deficient HT-29 cells under cultured conditions ( Figure 1 D).
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SMYD2 Inhibition Downregulates TMPRSS2 and Decreases SARS-CoV-2 Infection in Human Intestinal and Airway Epithelial Cells.
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