Compared with the control cells, HCCLM3 shPiezo1 and Hep3B shPiezo1 cells showed a decreasing trend in phosphorylation level of Smad2/3, which was similar to LY2109761 treated HCCLM3 shCtr and Hep3B shCtr cells.
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Piezo1 promoted hepatocellular carcinoma progression and EMT through activating TGF-β signaling by recruiting Rab5c.
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