Colchicine for COVID-19 in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial.

Br J Gen Pract · 2022 · PMC9037186 · PMID 35440469

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marginally significantno p-value reported

9 However, in a pre-specified secondary analysis among participants who were polymerase chain reaction (PCR) positive for SARS-CoV-2, there was a marginally significant reduction in COVID-19-related admissions to hospital and deaths compared with placebo (4.6% versus 6.0%; odds ratio (OR) 0.75, 95% confidence interval [CI] = 0.57 to 0.99, P = 0.042).

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