Lifestyle and Cardiovascular Risk Factors Associated With Heart Failure Subtypes in Postmenopausal Breast Cancer Survivors.

JACC CardioOncol · 2022 · PMC9040098 · PMID 35492810

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of borderline significanceno p-value reported

38 A history of diabetes was significantly associated with HFpEF, and a history of hypertension was of borderline significance, although these relationships did not persist after adjustment for multiple variables.

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borderline significantno p-value reported

Additionally, in age-adjusted models, HFpEF risk was associated with smoking history (HR: 1.74), diabetes (HR: 2.00), and MI history (HR: 3.33), and a borderline significant risk was associated with hypertension in the expected direction (HR: 1.90).

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marginally significantno p-value reported

In multivariable analysis, anthracycline chemotherapy was associated with a marginally significant 2.47-fold increased risk of HFrEF (95% CI: 0.94-6.46) that was not observed for HFpEF.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.