Although the rate of central metastases increased as the TSH level increased when compared in quartiles (quartile 1:36.4%, quartile 2: 36.4%, quartile 3: 22.7%, and quartile 4: 4.5%; p=0.055), the difference was close to significance.
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Relationship Between Thyroid-Stimulating Hormone Level and Aggressive Pathological Features of Papillary Thyroid Cancer.
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In addition, the risk of lymphovascular invasion was approximately 3 times higher in quartile 1 compared to quartile 4 (OR: 3.120, p=0.062), and although the difference was not significant, it was close to the limit of significance.