A novel superparamagnetic powerful guanidine-functionalized γ-Fe₂O₃ based sulfonic acid recyclable and efficient heterogeneous catalyst for microwave-assisted rapid synthesis of quinazolin-4(3<i>H</i>)-one derivatives in Green media.

However, regarding the low-cost and environment friendly criteria, multi-component reactions (MCRs), combining more than two components in a single synthetic operation, have gained ecological importance – aiming at synthesizing the highly significant chemical and biological organic frameworks.

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