Consistent with this hypothesis, a previous analysis of the proportion of patients experiencing a flare over the course of the study and the rate of flares by baseline OCS dosage (0, 0 to ≤5, 5> to ≤10, >10 mg/day), identified a possible trend for increased efficacy of mepolizumab in groups with higher baseline OCS dosage ( 9 ).
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Association Between Baseline Therapy and Flare Reduction in Mepolizumab-Treated Patients With Hypereosinophilic Syndrome.
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