Effects of Long-Term Enclosed Environment on Human Health Based on the Analysis of Salivary Microbiota and Cytokines.

Microbiol Spectr · 2022 · PMC9045383 · PMID 35254118

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a decreasing trendno p-value reported

an increasing trendno p-value reported

Furthermore, using the Mann-Kendall trend test ( 28 , 29 ) to analyze whether there was a trend change for the continuous period from normal environment into LP1, as shown in Table S3, IL-1β showed an increasing trend (except for subject A), IL-6 (except for subject B), IL-10, and TNF-α showed a decreasing trend, and IFN-γ kept a consistent level.

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