Spectral-domain OCT measurements in obesity: A systematic review and meta-analysis.

Patients with higher BMI had lower average pRNFL thickness with borderline significance (SMD: -0.26, 95% CI: -0.53 to 0.00, p = 0.05, S6 Fig ); however, none of the four quadrants had different thicknesses between the groups: superior pRNFL (SMD: -0.22, 95% CI: -0.54 to 0.11, p = 0.19), nasal pRNFL (SMD: -0.13, 95% CI: -0.47 to 0.21, p = 0.45), temporal pRNFL (SMD: -0.18, 95% CI: -0.45 to 0.10, p = 0.21), and inferior pRNFL (SMD: -0.08, 95% CI: -0.38 to 0.21, p = 0.58). 3.5.

also in 7,017 other papers

There was an overall trend towards decreased thickness in high BMI patients, but only two measurements reached statistical significance: temporal retinal nerve fiber layer (RNFL) (Standardized mean difference (SMD): -0.33, 95% confidence interval (CI): -0.53 to -0.14, p<0.01) and the choroidal region 1.0 mm nasal to fovea (SMD: -0.38, 95% CI: -0.60 to -0.16, p<0.01).

also in 4,871 other papers