In addition, compared to the respective controls, sg-ING4-2 or sg-ING4-3 dramatically suppressed the mRNA expression levels of OCT4, CD44, MYC, and NANOG in Ketr-3 cells, and decreased or showed a decreasing trend in the mRNA expression of OCT4, MYC, and NANOG in 786-O cells ( Figure 2B ).
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ING4 Promotes Stemness Enrichment of Human Renal Cell Carcinoma Cells Through Inhibiting DUSP4 Expression to Activate the p38 MAPK/type I IFN-Stimulated Gene Signaling Pathway.
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