Responsivity of the Striatal Dopamine System to Methylphenidate-A Within-Subject I-123-β-CIT-SPECT Study in Male Children and Adolescents With Attention-Deficit/Hyperactivity Disorder.

Front Psychiatry · 2022 · PMC9046584 · PMID 35492708

Europe PMC DOI

hedged sentences

0.0020

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantp = 0.002actually significant

Results On-MPH status was associated with a highly significant change (−29.9%) of striatal DAT BP as compared to off-MPH ( t = −4.12, p = 0.002).

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marginally non-significantp -value = 0.05actually significant

The change of the binding potential in the left putamen ( r = 0.64, p = 0.01) had a marginally non-significant stronger ( z = 1.57, p -value = 0.05) correlation with externalizing symptoms than the change of the binding potential of the right putamen ( r = 0.17, p = 0.58).

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