4 PRMTs and Immune Checkpoint Therapy Of the numerous immune checkpoints, the programmed death ligand-1/programmed death-1 (PD-L1/PD-1) signaling pathway is highly significant as it inhibits TCR-mediated T cell activation to regulate immune responses ( 191 ).
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Protein Arginine Methylation: An Emerging Modification in Cancer Immunity and Immunotherapy.
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