Moreover, CD8+ T cells showed an increasing trend within the tumor microenvironment ( Figure 4E ) in all the groups that underwent adenovirus-based treatment (Ad5/3Δ24, AdTRP2, and PeptiCRAd); however, a tendency in increased effector phenotype CXCR3+ among the CD8+ T cells was reported only in PeptiCRAd treated group ( Figure 4F ).
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