These parameters are highly significant from both a pathophysiological and a clinical point of view, as they are indicative of two major effort alterations of the disease, that is, low CO and altered exercise ventilation; moreover, peak VO 2 is the main CPET prognostic parameter for PAH patients.
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Role of cardiopulmonary exercise test in the prediction of hemodynamic impairment in patients with pulmonary arterial hypertension.
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