Effects of pharmacological treatment on metabolomic alterations in animal models of depression.

Transl Psychiatry · 2022 · PMC9055046 · PMID 35487889

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a decreasing trendno p-value reported

In this study, we found that pharmacological treatment increased central and circulating levels of tryptophan, while brain levels of quinolinic acid, kynurenine, and the kynurenine/tryptophan ratio showed a decreasing trend or statistically significant decrease.

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