highly significantP < 0.001
P < 0.05 were considered as statistically significant and labeled as *, while ** represents P < 0.01 (highly significant), and *** represents P < 0.001 (very highly significant), respectively.
P < 0.05 were considered as statistically significant and labeled as *, while ** represents P < 0.01 (highly significant), and *** represents P < 0.001 (very highly significant), respectively.