Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation.

With the caveat of the small group sizes, lung pathology scores had a highly significant inverse correlation with peak serum NT 50 values (Spearman r = -0.87; p < 0.001), followed by peak plasma VITROS anti-spike total Ig levels (Spearman r = -0.59, p = 0.046).

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