Barely Significant
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The Global Burden of Leukemia and Its Attributable Factors in 204 Countries and Territories: Findings from the Global Burden of Disease 2019 Study and Projections to 2030.

J Oncol · 2022 · PMC9061017 · PMID 35509847

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an increasing trendno p-value reported
However, an increasing trend was detected in the high-SDI regions (AAPC = 0.2, 95% CI 0.1 to 0.4).

also in 63,971 other papers

a decreasing trendno p-value reported
Notably, CML was the only leukemia subtype that showed a decreasing trend at the global level.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.