Barely Significant
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Macrocyclic pentamers functionalised around their periphery as potential building blocks.

RSC Adv · 2019 · PMC9061804 · PMID 35518683

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may be significantno p-value reported
Depending on the size of the macrocycle, the internal functionality may be significant in directing the formation of the macrocycle, or may be optimised for metal coordination or other guest recognition.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.