The Okur-Chung Neurodevelopmental Syndrome Mutation CK2^K198R Leads to a Rewiring of Kinase Specificity.

Finally, with regard to the phosphoacceptor residue, the phosphorylation sites unique to CK2 WT showed a highly significant disfavoring of tyrosine residues relative to serine residues that was lost in the CK2 K198R mutant (which displayed a general neutrality to the phosphoacceptor residue).

also in 132,142 other papers