Sensitive detection of methylated DNA and methyltransferase activity based on the lighting up of FAM-labeled DNA quenched fluorescence by gold nanoparticles.

RSC Adv · 2019 · PMC9063544 · PMID 35516994

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an increasing trendno p-value reported

The fluorescence intensity showed an increasing trend with M.SssI MTase enzyme activity in the range of 1–8 U mL −1 with a detection limit of 0.14 U mL −1 .

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