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Active targeting drug-gold nanorod hybrid nanoparticles for amplifying photoacoustic signal and enhancing anticancer efficacy.

RSC Adv · 2019 · PMC9064043 · PMID 35519580

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19,21,25 Therefore, it is highly significant to develop a nanoplatform able to protect the targeting ligand before entering into the tumor region and expose it only after entering the tumor. 29,30 Herein, an AuNR coated with a PA activating organic near-infrared dye IR780 and the anticancer drug doxorubicin (DOX) (AuNR@IR780/DOX) with high PA imaging performance for cancer imaging and therapy was developed, as displayed in Fig. 1 .

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