Barely Significant
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In-vitro NET-osis induced by COVID-19 sera is associated to severe clinical course in not vaccinated patients and immune-dysregulation in breakthrough infection.

Sci Rep · 2022 · PMC9065667 · PMID 35508575

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a positive trendno p-value reported
IL-1β was doubled in COVID-19 patients compared to healthy subjects, with a positive trend due to severity, in lack of statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.