The data obtained in the present work revealed that severe NPDR patients showed higher extent of both miR-146a and −21 by 283% and 345% accompanied with highly significant decrease in the level of miR-34a (by 70%) that its level reaches 30%compared to patients with normal fundus [ Fig. 7 C].
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MicroRNAs (-146a, -21 and -34a) are diagnostic and prognostic biomarkers for diabetic retinopathy.
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