Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases.

This result is in fact highly significant if this gel formulation is intended for the topical treatment of psoriasis, since this very concentration of CAGE-IL allowed the highest level of transdermal permeation of curcumin ( Fig. 4 ) for the highest level of curcumin integrated in the gel, while allowing saturation of the skin with the highest amount of curcumin ( Fig. 5 ).

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