Chicken CDS2 isoforms presented distinct spatio-temporal expression pattern and regulated by insulin in a breed-specific manner.

P < 0.05 was considered significant and P < 0.01 was considered extremely significant.

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The level of CDS2 -4 in the pectoralis at 21 d was significantly higher than that at the other ages tested, with the exception of 1 d ( P < 0.05); whereas hepatic CDS2 -4 levels presented a decreasing trend with development, with highest levels at the early stage of hatching (E10), a weak decrease during embryogenesis (E14–D1), and a clear decrease with age after hatching (D21 and D49, P = 0.009).

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