Ligand binding remodels protein side-chain conformational heterogeneity.

Elife · 2022 · PMC9084896 · PMID 35312477

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a small trendp=3.8 × 10 –20actually significant

Properties of the apo/holo pairs The median resolution across our dataset was 1.6 Å with a small trend towards improved (higher) resolution in the apo structure (0.01 Å, median improvement [holo-apo]; p=3.8 × 10 –20 , Wilcoxon signed-rank test; Figure 1—figure supplement 3A and B ).

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