ACU193: An Immunotherapeutic Poised to Test the Amyloid β Oligomer Hypothesis of Alzheimer's Disease.

Front Neurosci · 2022 · PMC9088393 · PMID 35557606

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a small trendno p-value reported

Two phase 3 studies (EXPEDITION and EXPEDITION2) did not achieve statistical significance on the primary outcome, but a small trend for slowing of progression was evident, with most secondary outcomes achieving nominal statistical significance ( Doody et al., 2014 ).

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